Hi Metro Csharp，
这个命题很大，很难详细的回答。
关于SQLite操作优化，可以参考一下StackOverflow上的一个讨论：
http://stackoverflow.com/questions/1711631/how-do-i-improve-the-performance-of-sqlite。 当然在 Windows Store App中 SQlite或许会有不同，不过大体的设置和操作都是一样的。
同时我找到一个Blog，或许对你有用（如果你使用这个Sqlite的扩展）： How to massively improve SQLite Performance (using SqlWinRT)
--James
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Thanks
MSDN Community Support
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