Hi Brian,
Thank you for posting in MSDN forum.
For reproducing this issue, I create a WinForm application, once I move the mouse, the dragdrop action stopped. this app works fine here:

Currently, we couldn't determine if the cause is related to your VS or your operating system slow.
You could try to replicate and import that scene into a new project or a new machine, to see if it is the same situation shows.
Then how about checking your OS running first, if the CPU taking memory is high, please go to Task Manager to kill some software and application you rarely use.
If the problem still persists, please feel free to tell us and we will try to figure out the reason why.
Best Regards,
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