Hi KZ,
From your description, my understanding is that you want to understand how to ensure 508 compliance on a SharePoint 2010 / 2013.
The link below is about section 508 Framework and SharePoint, you could learn something about some items that need to be considered:
section 508 Framework and SharePoint
http://www.armedia.com/blog/2013/06/section-508-compliance-and-sharepoint/
Here is a sample about SharePoint Forms and 508 Compliance for reference:
SharePoint Forms and 508 Compliance, Is it possible?
http://blog.helloitsliam.com/Lists/Posts/Post.aspx?ID=36
This article below is about SharePoint Usability and Accesibility Best Practices Including 508 Compliance, you could get the solution about
CSS validation returns errors in point 22:
SharePoint Usability and Accesibility Best Practices Including 508 Compliance - EPC group
http://www.slideshare.net/errino/sharepoint-usability-and-accesibility-best-practices-including-508-compliance-epc-group
Best Regards,
Vincent Han
TechNet Community Support
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