User-1087479560 posted
Hi,
First, you can refer to this documentation for how to use it with a database. http://ajax.asp.net/ajaxtoolkit/Walkthrough/CCDWithDB.aspx
Then, as far as I know, MySql provides db driver for .net which can be used in a similar way as the build-in ADO.NET does. You can download it from their website and try to implement it according to the above documentation.
Hope this helps.