Hello,
Any HL7 related artifact must run in a 32-bit host/host instance only. When using the MLLP/file adapter and HL7 pipelines, they must be set to run with the 32-bit host/host instance.
1) Can you pls ensure that the this port runs under a 32 bit host.
2) Remove and add BizTalk Application1 again as a reference to be able to see these pipeline enlisted.
Rachit Sikroria (Microsoft Azure MVP)