Could you clarify a bit on what you mean.
While the dataset is designed with a disconnected environment in mind, you will still have to be connected when interacting with your backend if a backend is used.
".NET Framework Developer's Guide - ADO.NET DataSets"
http://msdn.microsoft.com/en-us/library/zb0sdh0b.aspx".NET Framework Developer's Guide - ADO.NET Architecture"
http://msdn.microsoft.com/en-us/library/27y4ybxw.aspx
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