User844605415 posted
Are you trying to run the worker process as Wow64(32-bit)?
In that case there is a good chance that your configuration is trying to load some 64-bit isapi filter, for example aspnet_filter.dll,for v2.0, on a 64-bit OS there will be two instances of this dll on your machine under \framework and \framework64 folders.
You want to select the one under \framework.
Thanks,
Mukhtar Desai
IIS Performance Team