We are piloting CRM 4.0 rollup 7 in WS 2008 R2 and SQL 2008 all in one box. I do not know what we changed or modified that was not documented but we are now unable to publish any workflows. Several blog sites blame it on Rollup 2 modifing the web.config.
We have applied the suggested line <authorizedType Assembly="mscorlib, Version=2.0.0.0, Culture=neutral, PublicKeyToken=b77a5c561934e089" Namespace="System.Globalization" TypeName="CultureInfo" Authorized="True"/>
to the web.config and restarted IIS. But the problem is still there and we have no clue where to look at.